BDBM402238 (9aRS)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-2-(2,5- dimethylpyrazol-3-yl)-9a- methyl-4,9-dihydro-3H- pyrazino[1,2-c]pyrimidine- 1,6,8-trione::US10011607, 66

SMILES Cc1cc(N2CCN3C(=O)N(C(=O)CC3(C)C2=O)c2c(F)cc(cc2F)C#Cc2ccccc2)n(C)n1

InChI Key InChIKey=MECMXQWENVPJRF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402238   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM402238(US10011607, 66 | (9aRS)-7-[2,6-difluoro-4-(2- phen...)
Affinity DataEC50:  85nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent