BDBM402269 (9aS)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-9a- methyl-2-[(2-methylpyrazol- 3-yl)methyl]-4,9-dihydro-3H- pyrazino[1,2-c]pyrimidine- 1,6,8-trione::US10011607, 97

SMILES Cn1nccc1CN1CCN2C(=O)N(C(=O)C[C@@]2(C)C1=O)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=RGGMDYZYUCLESN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402269   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM402269(US10011607, 97 | (9aS)-7-[2,6-difluoro-4-(2- pheny...)
Affinity DataEC50:  76nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent