BDBM403487 US10335399, Example 3-9B::US10806724, Example 3-9B

SMILES C[C@H]1Cc2c(O[C@@H]1COC(F)F)nc(cc2-c1ccc(F)cc1F)C(N)=O

InChI Key InChIKey=PLFSBUVZIYVXAH-VXJOIVPMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403487   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403487(US10335399, Example 3-9B | US10806724, Example 3-9...)
Affinity DataIC50:  19nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403487(US10335399, Example 3-9B | US10806724, Example 3-9...)
Affinity DataIC50:  19nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent