BDBM403650 (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-(difluoromethyl)cyclopropyl]-18,18-difluoro-14-methoxy-3,6-dioxo-9-propyl-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide::US10335409, Example 60
SMILES CCC[C@@H]1[C@H](CN([C@@H]1C(=O)OC(C)(C)C)C(=O)[C@@H](NC(=O)O[C@@H]1C[C@H]1CCC=C)C(C)(C)C)Oc1nc2cc(OC)ccc2nc1C(F)(F)C=C
InChI Key InChIKey=UQXWQVNCVWOJOI-IMGPWNAVSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 403650
Affinity DataKi: 0.0400nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair