BDBM404521 (R)-N-(1-cyanopyrrolidin-3-yl)-5-(4-fluorophenyl)picolinamide::US10343992, Example 173::US11390584, Example 173

SMILES Fc1ccc(cc1)-c1ccc(nc1)C(=O)N[C@@H]1CCN(C1)C#N

InChI Key InChIKey=GUPSFTJGPXXICE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404521   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM404521((R)-N-(1-cyanopyrrolidin-3-yl)-5-(4-fluorophenyl)p...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM404521((R)-N-(1-cyanopyrrolidin-3-yl)-5-(4-fluorophenyl)p...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
US Patent