BDBM404620 (R)-N-(1- cyanopyrrolidin- 3-yl)-3-(2,4- difluorophenyl) isoxazole-5- carboxamide::US10343992, Example 272::US11066365, Example 272

SMILES Fc1ccc(-c2cc(on2)C(=O)N[C@@H]2CCN(C2)C#N)c(F)c1

InChI Key InChIKey=VPLQNBYFNUEOOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404620   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Missions Therapeutics

US Patent
LigandPNGBDBM404620((R)-N-(1- cyanopyrrolidin- 3-yl)-3-(2,4- difluorop...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Missions Therapeutics

US Patent
LigandPNGBDBM404620((R)-N-(1- cyanopyrrolidin- 3-yl)-3-(2,4- difluorop...)
Affinity DataIC50: 100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2021
Entry Details
US Patent