BDBM405044 1-(4-{4-[2-(5-chloro-2- fluorophenyl)acetamido]-1H-1,2,3- triazol-1-yl}butyl)-N-[(6- methylpyridin-3-yl)methyl]-1H-1,2,3- triazole-4-carboxamide::US10344025, Example 388::US11370786, Example 388

SMILES Cc1ccc(CNC(=O)c2cn(CCCCn3cc(NC(=O)Cc4cc(Cl)ccc4F)nn3)nn2)cn1

InChI Key InChIKey=GOGWJNHDRCIWNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405044   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405044(US10344025, Example 388 | 1-(4-{4-[2-(5-chloro-2- ...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405044(US10344025, Example 388 | 1-(4-{4-[2-(5-chloro-2- ...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent