BDBM405225 1-(4-(5-(cyclopropanecarboxamido)- 1,3,4-thiadiazol-2-yl)-2-fluorobutyl)- N-((4-(trifluoromethyl)pyridin-2- yl)methyl)-1H-1,2,3-triazole-4- carboxamide::US10344025, Example 569::US11370786, Example 569

SMILES FC(CCc1nnc(NC(=O)C2CC2)s1)Cn1cc(nn1)C(=O)NCc1cccc(c1)C(F)(F)F

InChI Key InChIKey=TZPMEEHVJKJNAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405225   

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405225(1-(4-(5-(cyclopropanecarboxamido)- 1,3,4-thiadiazo...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405225(1-(4-(5-(cyclopropanecarboxamido)- 1,3,4-thiadiazo...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent