BDBM405229 1-(2-fluoro-4-(5-(2-(thiazol-2- yl)acetamido)-1,3,4-thiadiazol-2- yl)butyl)-N-(2-fluoro-5- (trifluoromethoxy)benzyl)-1H-1,2,3- triazole-4-carboxamide::US10344025, Example 573::US11370786, Example 573

SMILES FC(CCc1nnc(NC(=O)Cc2nccs2)s1)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F

InChI Key InChIKey=LAVLTLAWVOSZHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405229   

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405229(1-(2-fluoro-4-(5-(2-(thiazol-2- yl)acetamido)-1,3,...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405229(1-(2-fluoro-4-(5-(2-(thiazol-2- yl)acetamido)-1,3,...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent