BDBM405243 1-(4-(6-(2-(2-fluoro-5- (trifluoromethoxy)phenyl)acetamido) pyridazin-3-yl)butyl)-N-(pyridin-4- ylmethyl)-1H-1,2,3-triazole-4- carboxamide::US10344025, Example 587::US11370786, Example 587

SMILES Fc1ccc(OC(F)(F)F)cc1CC(=O)Nc1ccc(CCCCn2cc(nn2)C(=O)NCc2ccncc2)nn1

InChI Key InChIKey=OGOSCMXCBSBEJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405243   

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405243(1-(4-(6-(2-(2-fluoro-5- (trifluoromethoxy)phenyl)a...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405243(1-(4-(6-(2-(2-fluoro-5- (trifluoromethoxy)phenyl)a...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent