BDBM405247 1-4-(6- (cyclopropanecarboxamido)pyridazin- 3-yl)butyl)-N-(2-fluoro-5- (trifluoromethoxy)benzyl)-1H-1,2,3- triazole-4-carboxamide::US10344025, Example 591::US11370786, Example 591

SMILES Fc1ccc(OC(F)(F)F)cc1CNC(=O)c1cn(CCCCc2ccc(NC(=O)C3CC3)nn2)nn1

InChI Key InChIKey=HWKMCHXILOSSFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405247   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405247(1-4-(6- (cyclopropanecarboxamido)pyridazin- 3-yl)b...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405247(1-4-(6- (cyclopropanecarboxamido)pyridazin- 3-yl)b...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent