BDBM405261 N-methyl-1-(4-(6-(2-(4-(2- (trifluoromethyl)phenyl)pyridin-2- yl)acetamido)pyridazin-3-yl)butyl)- 1H-1,2,3-triazole-4-carboxamide::US10344025, Example 605::US11370786, Example 605

SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(ccn3)-c3ccccc3C(F)(F)F)nn2)nn1

InChI Key InChIKey=KQBJSQBMOJNCJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405261   

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405261(N-methyl-1-(4-(6-(2-(4-(2- (trifluoromethyl)phenyl...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405261(N-methyl-1-(4-(6-(2-(4-(2- (trifluoromethyl)phenyl...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent