BDBM405533 USRE47493, Example 75.6

SMILES COCCNC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)[C@H]1c1ccc(C#N)cc1S(C)(O)O

InChI Key InChIKey=RKPVPXDNBMWSLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 405533   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 405533BDBM405533(USRE47493, Example 75.6)
Affinity DataIC50: 1nMAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat.No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bache...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
US Patent