BDBM405594 US10351547, Compound 2-8::US10597377, Compound 2-8

SMILES Cc1cc(F)cc(-c2cnc3ccc(-c4cccc5[nH]c(=O)[nH]c45)cc3c2N2CCC(N)CC2)c1

InChI Key InChIKey=NYDNSRSLDMWKHR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405594   

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 405594BDBM405594(US10351547, Compound 2-8 | US10597377, Compound 2-...)
Affinity DataEC50: <10nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC # CCL-61) stably expressing the human SSTR2 are plated in each well of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 405594BDBM405594(US10351547, Compound 2-8 | US10597377, Compound 2-...)
Affinity DataEC50: <10nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human SSTR2 are plated in each well of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details
US Patent