BDBM406351 US10336731, Compound 2, racemic

SMILES C[C@H]1CC1(NC(=O)c1cc2cc(Br)ccc2[nH]1)c1cnn(C)c1

InChI Key InChIKey=DWNWOEPUWVBYQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406351   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM406351(US10336731, Compound 2, racemic)
Affinity DataIC50: 398nMAssay Description:0.17 μM of human IDO protein was pre-incubated for 120 min at RT with test compounds in the presence of 50 mM KPO4, pH 7.0, 0.5 mM EDTA, 0.5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent