BDBM406353 US10336731, Compound 4

SMILES CC(C)c1nn(C)cc1C1(CC1)NC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key InChIKey=ZQGOQQSTWYHYBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406353   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM406353(US10336731, Compound 4)
Affinity DataIC50: 447nMAssay Description:0.17 μM of human IDO protein was pre-incubated for 120 min at RT with test compounds in the presence of 50 mM KPO4, pH 7.0, 0.5 mM EDTA, 0.5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent