BDBM406407 US10336734, Example 20

SMILES COc1cc(ccc1Nc1ncc(Cl)c(NCCc2c(F)cccc2Cl)n1)N1CCN(C)CC1

InChI Key InChIKey=DKNACWKOKCXDEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 406407   

TargetALK tyrosine kinase receptor(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406407(US10336734, Example 20)
Affinity DataIC50: 7nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406407(US10336734, Example 20)
Affinity DataIC50: 27nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406407(US10336734, Example 20)
Affinity DataIC50: 1.72E+3nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406407(US10336734, Example 20)
Affinity DataIC50: 1.15E+4nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent