BDBM406408 US10336734, Example 21

SMILES COc1ccccc1CCNc1nc(Nc2ccc(cc2OC)N2CCN(C)CC2)ncc1Cl

InChI Key InChIKey=JJBNBDJXYZZFBC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 406408   

TargetALK tyrosine kinase receptor(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406408(US10336734, Example 21)
Affinity DataIC50: 2nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406408(US10336734, Example 21)
Affinity DataIC50: 24nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406408(US10336734, Example 21)
Affinity DataIC50: 860nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM406408(US10336734, Example 21)
Affinity DataIC50: 8.25E+3nMAssay Description:Enzyme-Linked Immunosorbent Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent