BDBM406553 6-butyl-4-hydroxy- 3-{5-[(2-methyl- 1,3-thiazol-4- yl)methyl]-1,3,4- oxadiazol-2-yl}-5- [3-(propan-2- yl)phenyl]-1,2- dihydropyridin-2- one::US10336739, Example 148

SMILES CCCCc1nc(O)c(-c2nnc(Cc3ccc(F)c(F)c3)o2)c(O)c1-c1cccc(c1)C(=O)NC(C)C

InChI Key InChIKey=QKXNXBVTJUVDHC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406553   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406553(6-butyl-4-hydroxy- 3-{5-[(2-methyl- 1,3-thiazol-4-...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent