BDBM406554 3-(2-butyl-4- hydroxy-5-{5-[(2- methyl-1,3-thiazol- 4-yl)methyl]-1,3,4- oxadiazol-2-yl}-6- oxo-1,6- dihydropyridin-3- yl)-N-(propan-2- yl)benzamide::US10336739, Example 149

SMILES CCCCc1[nH]c(=O)c(-c2nnc(Cc3csc(C)n3)o2)c(O)c1-c1cccc(CC)c1

InChI Key InChIKey=BQIZDKBOPHTRFY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406554   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406554(3-(2-butyl-4- hydroxy-5-{5-[(2- methyl-1,3-thiazol...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent