BDBM408192 N-(2-(4-(1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethyl)piperazin-1-yl)pyrimidin-5-yl)acetamide::US10336775, Example 96::US11046712, No 96

SMILES CC(N1CCN(CC1)c1ncc(NC(C)=O)cn1)c1ccc2OCCOc2c1

InChI Key InChIKey=MYSCAJNXBXOPDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408192   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408192(N-(2-(4-(1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)et...)
Affinity DataIC50: 50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408192(N-(2-(4-(1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)et...)
Affinity DataIC50: 50nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent