BDBM408260 (S)-1-(2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-5(4H)-yl)ethan-1-one::US10336775, Example 184::US11046712, No 184

SMILES C[C@H](N1CCN(CC1)c1nc2CCN(Cc2s1)C(C)=O)c1ccc2OCOc2c1

InChI Key InChIKey=WLRURMROMALESO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408260   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408260((S)-1-(2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pip...)
Affinity DataIC50: 50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408260((S)-1-(2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pip...)
Affinity DataIC50: 50nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent