BDBM408264 (S)-4-(2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)pyrimidin-5-yl)tetrahydro-2H-pyran-4-ol::US10336775, Example 188::US11046712, No 188

SMILES C[C@H](N1CCN(CC1)c1ncc(cn1)C1(O)CCOCC1)c1ccc2OCOc2c1

InChI Key InChIKey=YTURMRWJSNPQAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408264   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408264((S)-4-(2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pip...)
Affinity DataIC50: 50nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408264((S)-4-(2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pip...)
Affinity DataIC50: 50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent