BDBM408270 (S)-2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-d]pyridine::US10336775, Example 194::US11046712, No 194

SMILES C[C@H](N1CCN(CC1)c1nc2CCN(C)Cc2s1)c1ccc2OCOc2c1

InChI Key InChIKey=GHZQEGHHKPPLRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408270   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408270((S)-2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pipera...)
Affinity DataIC50: 50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408270((S)-2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pipera...)
Affinity DataIC50: 50nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent