BDBM408482 4-ethynyl-6-methoxy-2- methylpyrimidine::US10358435, Example 4

SMILES COc1cc(nc(C)n1)C#C

InChI Key InChIKey=MDJXNPMQJXFRMO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408482   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 408482BDBM408482(4-ethynyl-6-methoxy-2- methylpyrimidine | US103584...)
Affinity DataKi:  1.03E+3nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent