BDBM408493 1-(1-azidoethyl)-2,3- difluoro-4-(trifluoromethyl) benzene::US10358435, Example 14

SMILES CC(N=[N+]=[N-])c1ccc(c(F)c1F)C(F)(F)F

InChI Key InChIKey=DMWNFHJSGBNZSM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408493   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408493(1-(1-azidoethyl)-2,3- difluoro-4-(trifluoromethyl)...)
Affinity DataKi:  20.9nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408493(1-(1-azidoethyl)-2,3- difluoro-4-(trifluoromethyl)...)
Affinity DataKi:  24.9nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent