BDBM408658 4-(azetidin-1-yl)-2- oxo-1,2- dihydroquinoline-3- carbonitrile::US10376504, Example 1-9

SMILES N#Cc1c(N2CCC2)c2ccccc2[nH]c1=O

InChI Key InChIKey=HZJISVRJZJAESR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408658   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 408658BDBM408658(US10376504, Example 1-9 | 4-(azetidin-1-yl)-2- oxo...)
Affinity DataKi:  5.55E+3nMAssay Description:Rhesus PDE9A2 was amplified from rhesus whole brain cDNA (Biochain Institute) essentially as described in Hutson, et al. Neuropharmacology (2011) 61(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details
US Patent