BDBM408662 4-((2-(oxetan-3- yl)ethyl)amino)-2- oxo-1,2- dihydroquinoline-3- carbonitrile::US10376504, Example 1-12

SMILES O=c1[nH]c2ccccc2c(NCCC2COC2)c1C#N

InChI Key InChIKey=MDWUVFIJMZRNCQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408662   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408662(US10376504, Example 1-12 | 4-((2-(oxetan-3- yl)eth...)
Affinity DataKi:  71.1nMAssay Description:Rhesus PDE9A2 was amplified from rhesus whole brain cDNA (Biochain Institute) essentially as described in Hutson, et al. Neuropharmacology (2011) 61(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details
US Patent