BDBM408819 US10364255, Ex. 11::US10364255, Ex. 12

SMILES O=C(N1CCC(C1)c1ccncc1)c1cnc2N[C@H](COc2c1)c1ccccc1

InChI Key InChIKey=ISCNEHUAWLGHPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408819   

TargetPantetheinase(Human)
Boehringer Ingleheim International

US Patent
LigandPNGBDBM408819(US10364255, Ex. 12 | US10364255, Ex. 11)
Affinity DataIC50: 1.80nMAssay Description:Method 1:Vanin-1 Enzymatic Assay:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details
US Patent

TargetPantetheinase(Human)
Boehringer Ingleheim International

US Patent
LigandPNGBDBM408819(US10364255, Ex. 12 | US10364255, Ex. 11)
Affinity DataIC50: 19nMAssay Description:Method 1:Vanin-1 Enzymatic Assay:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details
US Patent