BDBM408958 Isopropyl 1-(N-((trans-4-(4-methoxy-3-methylphenyl)cyclohexyl)methyl)-3,3-dimethylbutanamido)isoquinoline-6-carboxylate::US10377717, Compound 87

SMILES COc1ccc([C@H]2CC[C@H](CN(C(=O)CC(C)(C)C)c3nccc4cc(C(=O)OC(C)C)ccc34)CC2)cc1C

InChI Key InChIKey=DKTLBQSKGUSPIY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408958   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408958BDBM408958(Isopropyl 1-(N-((trans-4-(4-methoxy-3-methylphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent