BDBM408962 Methyl 1-(3,3-dimethyl-N-((trans-4-(p- tolyl)cyclohexyl) methyl)butanamido)isoquinoline- 6-carboxylate::US10377717, Compound 91

SMILES COC(=O)c1ccc2c(N(C[C@H]3CC[C@H](c4ccc(C)cc4)CC3)C(=O)CC(C)(C)C)nccc2c1

InChI Key InChIKey=SNNAGKCZOWLVKC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408962   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandChemical structure of BindingDB Monomer ID 408962BDBM408962(Methyl 1-(3,3-dimethyl-N-((trans-4-(p- tolyl)cyclo...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent