BDBM409775 US10370333, Example I-4

SMILES COc1cc(C)ccc1S(=O)(=O)Nc1cccnc1

InChI Key InChIKey=LZWDXCJPPLHLQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 409775   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409775(US10370333, Example I-4)
Affinity DataIC50: <100nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409775(US10370333, Example I-4)
Affinity DataIC50:  3.55E+3nMAssay Description:Inhibition of TNAP (unknown origin) in whole blood using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409775(US10370333, Example I-4)
Affinity DataIC50:  896nMAssay Description:Inhibition of TNAP (unknown origin) using PPi as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed