BDBM409783 4-(2-naphthyl)- 2-oxo-1H- quinoline-3- carbonitrile::US10370336, Example 1-10

SMILES Oc1nc2ccccc2c(-c2ccc3ccccc3c2)c1C#N

InChI Key InChIKey=SNYRFBLVJOSZMJ-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409783   

TargetIsoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A2)(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM409783(4-(2-naphthyl)- 2-oxo-1H- quinoline-3- carbonitril...)Copy SMILESCopy InChI

Affinity DataKi:  14.8nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/6/2020
Entry Details
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