BDBM409949 4-(2-fluoro- 4-methyl- phenyl)-2- oxo-1H- quinoline-3- carbonitrile::US10370336, Example 1-11

SMILES Cc1ccc(c(F)c1)-c1c(C#N)c(=O)[nH]c2ccccc12

InChI Key InChIKey=YKGAOVJEHVZMCO-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409949   

TargetIsoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A2)(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM409949(4-(2-fluoro- 4-methyl- phenyl)-2- oxo-1H- quinolin...)Copy SMILESCopy InChI

Affinity DataKi:  7.20nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/6/2020
Entry Details
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