BDBM409968 4-((3-allyl- oxetan-3-yl) methoxy)-2- oxo-1,2- dihydro- quinoline- 3-carbonitrile::US10370337, Example 1-11

SMILES C=CCC1(COc2c(C#N)c(=O)[nH]c3ccccc23)COC1

InChI Key InChIKey=HGHIOURTTPUKKC-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409968   

TargetIsoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A2)(Human)
Merck, Sharp & Dohme

US Patent

LigandBDBM409968(4-((3-allyl- oxetan-3-yl) methoxy)-2- oxo-1,2- dih...)Copy SMILESCopy InChI

Affinity DataKi:  87.8nMAssay Description:Human PDE9 (PDE9A2, GenBank Accession No. NM_001001567), full length with N-terminal GST tag, was purchased from BPS Bioscience. The fluorescence pol...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/6/2020
Entry Details
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