BDBM410182 US10377763, Compound 3::tert-butyl(4R,4aS,7R,7aR,12bS)-7-[benzyl(methyl)amino]-4a-hydroxy-9-methoxy-1,2,4,4a,5,6,7,7a-octahydro-3H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-carboxylate

SMILES COc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)N(C)Cc1ccccc1)C(=O)OC(C)(C)C

InChI Key InChIKey=WEEKNFOHQODTPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410182   

TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

US Patent
LigandPNGBDBM410182(tert-butyl(4R,4aS,7R,7aR,12bS)-7-[benzyl(methyl)am...)
Affinity DataIC50: 2.85E+3nMAssay Description:The Chinese hamster ovary (CHO) cell lines CHOOX1R and CHOOX2R were established by modifying CHO cells to constantly express the NFAT-luciferase gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
University of Tsukuba

US Patent
LigandPNGBDBM410182(tert-butyl(4R,4aS,7R,7aR,12bS)-7-[benzyl(methyl)am...)
Affinity DataIC50: 1.00E+4nMAssay Description:The Chinese hamster ovary (CHO) cell lines CHOOX1R and CHOOX2R were established by modifying CHO cells to constantly express the NFAT-luciferase gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent