BDBM410251 (E)-N-[(4R,4aS,7R,7aR,12bS)-3-{[2-(dimethylamino) phenyl]sulfonyl}-4a-hydroxy-9-methoxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-N-methyl-3-(pyridin-2-yl)acrylamide ::US10377763, Example 45

SMILES COc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C1(CC[C@@]35O)OCCO1)S(=O)(=O)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=CAJZNNKEDNNELH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410251   

TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

US Patent
LigandPNGBDBM410251((E)-N-[(4R,4aS,7R,7aR,12bS)-3-{[2-(dimethylamino) ...)
Affinity DataIC50: 3.61nMAssay Description:The Chinese hamster ovary (CHO) cell lines CHOOX1R and CHOOX2R were established by modifying CHO cells to constantly express the NFAT-luciferase gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
University of Tsukuba

US Patent
LigandPNGBDBM410251((E)-N-[(4R,4aS,7R,7aR,12bS)-3-{[2-(dimethylamino) ...)
Affinity DataIC50: 1.00E+4nMAssay Description:The Chinese hamster ovary (CHO) cell lines CHOOX1R and CHOOX2R were established by modifying CHO cells to constantly express the NFAT-luciferase gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent