BDBM411186 Methyl 2-(N-(2-methoxy-3,4′-bipyridin-3′-yl)-2,6-bis(trifluoromethyl)isonicotinamido)acetate::US10385022, Example 182

SMILES COC(=O)CN(C(=O)c1cc(nc(c1)C(F)(F)F)C(F)(F)F)c1cnccc1-c1cccnc1OC

InChI Key InChIKey=CTGLCMHNBOJDEU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411186   

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM411186(Methyl 2-(N-(2-methoxy-3,4′-bipyridin-3̸...)
Affinity DataEC50:  27nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent