BDBM411209 N-[4-(2-Fluoro-6-methoxy-phenyl)-pyridin-3-yl]-3-methanesulfonyl-N-methyl-5-trifluoromethyl-benzamide::US10385022, Example 205

SMILES COc1cccc(F)c1-c1ccncc1N(C)C(=O)c1cc(cc(c1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=HJZRBTWBJUSFQI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411209   

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM411209(N-[4-(2-Fluoro-6-methoxy-phenyl)-pyridin-3-yl]-3-m...)
Affinity DataEC50:  17nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent