BDBM411255 N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-methyl-3-(oxetan-3-ylsulfanyl)-5-trifluoromethyl-benzamide::US10385022, Example 251

SMILES COc1cc(F)ccc1-c1ccncc1N(C)C(=O)c1cc(SC2COC2)cc(c1)C(F)(F)F

InChI Key InChIKey=AIUKMVPZCKWMFY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411255   

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM411255(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-m...)
Affinity DataEC50:  30nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent