BDBM411307 3-Bromo-N-[4-(4-fluoro-2-methoxy-phenyl)-6-methyl-pyridin-3-yl]-N-methyl-5-trifluoromethyl-benzamide::US10385022, Example 303

SMILES COc1cc(F)ccc1-c1cc(C)ncc1N(C)C(=O)c1cc(Br)cc(c1)C(F)(F)F

InChI Key InChIKey=UCVIAFNGZLWQLS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411307   

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM411307(3-Bromo-N-[4-(4-fluoro-2-methoxy-phenyl)-6-methyl-...)
Affinity DataEC50:  18nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent