BDBM411387 N-(3-((3R,4R)-1-(cyclopentanecarbonyl)-3- methylpiperidin-4-yl)-1-methyl-1H-indol-5-yl)- 4-fluorobenzenesulfonamide.::US10385036, Example 3

SMILES C[C@H]1CN(CC[C@H]1c1cn(C)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12)C(=O)C1CCCC1

InChI Key InChIKey=LMLXETLMKQLISE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411387   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411387(US10385036, Example 3 | N-(3-((3R,4R)-1-(cyclopent...)
Affinity DataIC50: 5.30nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent