BDBM411390 Preparation of 4-fluoro-N-(3-(1-(isothiazole-5-carbonyl)piperidin-4-yl)-1-methyl-1H-indol-5-yl)benzenesulfonamide::US10385036, Example 6

SMILES Cn1cc(C2CCN(CC2)C(=O)c2ccns2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12

InChI Key InChIKey=ISULHBUWFIAJCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411390   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411390(US10385036, Example 6 | Preparation of 4-fluoro-N-...)
Affinity DataIC50: 75.9nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent