BDBM411393 4-fluoro-N-(1-methyl-3-(1-(4,4,4-trifluoro-3- methylbutanoyl)piperidin-4-yl)-1H-indol-5- yl)benzenesulfonamide::US10385036, Example 9

SMILES CC(CC(=O)N1CCC(CC1)c1cn(C)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12)C(F)(F)F

InChI Key InChIKey=ROFWCJDZFLNSEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411393   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411393(US10385036, Example 9 | 4-fluoro-N-(1-methyl-3-(1-...)
Affinity DataIC50: 14.8nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent