BDBM411406 Preparation of 4-fluoro-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-1H-indol-5-yl)-3-methoxybenzenesulfonamide::US10385036, Example 22

SMILES COc1cc(ccc1F)S(=O)(=O)Nc1ccc2n(C)cc(C3CCN(CC3)C(=O)C(C)C)c2c1

InChI Key InChIKey=UBAWRLQVCCPNAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411406   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM411406(US10385036, Example 22 | Preparation of 4-fluoro-N...)
Affinity DataIC50: 10.6nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
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Date in BDB:
7/13/2020
Entry Details
US Patent