BDBM411458 US10385066, Example 23

SMILES COc1ccccc1-n1ccc2cc(cc(NC(=O)C3CC3)c12)N1CCOc2ncnc(Cl)c2C1=O

InChI Key InChIKey=MIEOXKMVBPYEMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411458   

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411458(US10385066, Example 23)
Affinity DataIC50: 16.1nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent