BDBM411462 US10385066, Example 36

SMILES COc1cccc(c1Br)-n1ccc2cc(ccc12)N1CCOc2ncnc(Cl)c2C1=O

InChI Key InChIKey=DPJFZHLAEMDWBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411462   

TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM411462(US10385066, Example 36)
Affinity DataIC50:  1.80nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent