BDBM412207 US10398703, Compound 54::US10966987, Compound 54

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccccc4CN4CCN(C)CC4)c(Cl)c3)c2cc1OC

InChI Key InChIKey=SDXJBVJNXXJYRE-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412207   

TargetVascular endothelial growth factor receptor 2(Human)
Kala Pharmaceuticals

US Patent
LigandPNGBDBM412207(US10398703, Compound 54 | US10966987, Compound 54)
Affinity DataKd:  2.70E+4nMAssay Description:A VEGFR2 tagged T7 phage strain was prepared in an Escherichia coli (E. coli) derived from the BL21 strain. The E. coli were grown to log-phase, infe...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Kala Pharmaceuticals

US Patent
LigandPNGBDBM412207(US10398703, Compound 54 | US10966987, Compound 54)
Affinity DataKd:  2.70E+4nMAssay Description:A competition binding assay (DISCOVERX KINOMESCAN ) was used to measure the ability of a compound to compete for binding of an immobilized adenosine ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent