BDBM412287 US10399945, Example 26::US10669239, Compound 26::US10927079, Compound 26

SMILES Cc1cnc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1

InChI Key InChIKey=DCZVZWOAEFCOIJ-IFMALSPDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412287   

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412287(US10399945, Example 26 | US10669239, Compound 26 |...)
Affinity DataIC50: <50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent


TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412287(US10399945, Example 26 | US10669239, Compound 26 |...)
Affinity DataIC50: <0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent


TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412287(US10399945, Example 26 | US10669239, Compound 26 |...)
Affinity DataIC50: <50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent