BDBM412293 US10399945, Example 32::US10927079, Compound 32

SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccc(Br)cc23)c1)-c1ccccc1

InChI Key InChIKey=AICYKKCIWBCNKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412293   

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412293(US10399945, Example 32 | US10927079, Compound 32)
Affinity DataIC50: 0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412293(US10399945, Example 32 | US10927079, Compound 32)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent